Hydroxyurea can result in a significant lessen in the volume of blood cells as part of your bone marrow. This may increase the possibility that you're going to develop a significant infection or bleeding. When you working experience any of the next indications, call your doctor quickly: fever, chills, extreme tiredness or weakness, physique aches,
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Contraindicated (one)bortezomib will boost the degree or effect of mavacamten by impacting hepatic enzyme CYP2C19 metabolism. Contraindicated. Sturdy or reasonable CYP2C19 inhibitors may possibly maximize mavacamten systemic exposure, resulting in coronary heart failure due to systolic dysfunction.Consequently, there is an excellent smaller proper